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Relationship between muscle stability and MPO gene polymorphisms: clinical implications in frailty and aging
Frailty and functional decline in older adults are closely linked to the loss of muscle stability. Several studies have suggested that the predisposition to these phenotypes could be modulated by genetic factors, including polymorphisms in the MPO (myeloperoxidase) gene, an enzyme linked to oxidative stress and inflammation. This paper explores the current evidence on the relationship between muscle stability and MPO gene variants, with implications for the early identification of frailty risk and the design of personalized preventive strategies [1,2].