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CAR-NK cells: an emerging therapy in immuno-oncology
Cellular immunotherapy has revolutionized cancer treatment, especially through the use of chimeric antigen receptor T cells (CAR-T cells). However, CAR-modified natural killer (NK) cells are emerging as a promising alternative with significant advantages in safety, feasibility, and clinical applicability. This paper explores the current status of CAR-NK therapy development, their comparison with CAR-T, potential applications in hematological and solid tumors, and the main regulatory and manufacturing challenges facing this technology [1,2].