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Immunotherapy, Chronic Diseases, Hematology, Microbiology, and Biotechnology: Scientific Advances and Clinical Applications
Biomedical and biotechnological research has significantly advanced in key areas such as cancer immunotherapy, the impact of chronic diseases on neuroscience, hematology, antimicrobial resistance, and microbial production. In oncology, natural killer cells with chimeric antigen receptor (CAR-NK) have emerged as a promising strategy against cancer. In chronic diseases, the relationship between type 2 diabetes mellitus and cognitive decline has been demonstrated, as well as the influence of body composition on cognitive processing speed. In hematology, the ABO phenotype has been linked to hematological and non-hematological diseases. Clinical microbiology has raised concerns about antimicrobial resistance, with studies on resistant bacteria in blood cultures, the antimicrobial potential of plant extracts, and the use of Caenorhabditis elegans as an infection model. Finally, in biotechnology, astaxanthin production and the study of xerophilic microorganisms reinforce the industrial potential of microbiology. This paper reviews these advances and their implications for health and biotechnology.