Published 2022-12-31
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Artículos

Inmunotherapy, Cancer, Genetics, and Clinical Microbiology: Chimeric Antigen Receptor Natural Killer (CAR-NK) Cells, ABO Phenotype, and Antimicrobial Resistance

DOI: https://doi.org/10.22490/ECISA.9377
Luz Mery Bernal Parra universidad nacional abierta y a distancia

Inmunotherapy has revolutionized cancer treatment, and one of the most promising strategies is the use of natural killer cells modified with chimeric antigen receptors (CAR-NK). These cells combine the specificity of CAR receptors with the innate cytotoxic capacity of NK cells, offering an effective and safe alternative to other immunotherapeutic treatments. Additionally, the ABO phenotype has been associated with various hematological and non-hematological diseases, suggesting a relevant role of genetics in disease predisposition. Moreover, antimicrobial resistance has become a critical issue in clinical microbiology, requiring new strategies to combat resistant infections. This paper analyzes recent advances in CAR-NK therapy, the impact of the ABO phenotype on hematological diseases, and research on antimicrobial resistance, including new therapeutic approaches and experimental models.

keywords: Inmunoterapia, CAR-NK, células asesinas naturales, terapia contra el cáncer, receptores de antígeno, microbiología clínica., fenotipo ABO, resistencia antimicrobiana, enfermedades hematológicas
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How to Cite

Bernal Parra, L. M. (2022). Inmunotherapy, Cancer, Genetics, and Clinical Microbiology: Chimeric Antigen Receptor Natural Killer (CAR-NK) Cells, ABO Phenotype, and Antimicrobial Resistance: Células Asesinas Naturales con Receptor de Antígeno Quimérico (CAR-NK), Fenotipo ABO y Resistencia Antimicrobiana. Documentos De Trabajo ECISA, 4. https://doi.org/10.22490/ECISA.9377
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