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The Inner Battle of Cancer: Unraveling Resistance to Chemotherapy
The phenomenon of chemotherapy resistance represents one of the greatest challenges in the fight against cancer. This paper analyzes the molecular mechanisms that allow tumor cells to evade drug action, with emphasis on overexpression of efflux pumps and dysfunction in apoptotic pathways. Understanding these processes is essential for the development of combination therapies that overcome resistance and improve the efficacy of oncology treatment (1-22).